Handbook on Microsystems for Enhanced Control of Cell Behavior, Andrés Díaz Lantada, Springer 2016: This handbook focuses on the entire development process of biomedical microsystems that promote special interactions with cells. Fundamentals of cell biology and mechanobiology are described as necessary preparatory input for design tasks. Advanced design, simulation, and micro/nanomanufacturing resources, whose combined use enables the development of biomedical microsystems capable of interacting at a cellular level, are covered in depth. A detailed series of chapters is then devoted to applications based on microsystems that offer enhanced cellular control, including microfluidic devices for diagnosis and therapy, cell-based sensors and actuators (smart biodevices), microstructured prostheses for improvement of biocompatibility, microstructured and microtextured cell culture matrices for promotion of cell growth and differentiation, electrophoretic microsystems for study of cell mechanics, microstructured and microtextured biodevices for study of cell adhesion and dynamics, and biomimetic microsystems (including organs-on-chips), among others.
Handbook on Advanced Design and Manufacturing Technologies for Bio-medical Devices, Andrés Díaz Lantada, Springer 2014: The last decades have seen remarkable advances in computer‐aided design, engineering and manufacturing technologies, multi‐variable simulation tools, medical imaging, biomimetic design, rapid prototyping, micro and nanomanufacturing methods and information management resources, all of which provide new horizons for the Biomedical Engineering fields and the Medical Device Industry. Advanced Design and Manufacturing Technologies for Biomedical Devices covers such topics in depth, with an applied perspective and providing several case studies that help to analyze and understand the key factors of the different stages linked to the development of a novel biomedical device, from the conceptual and design steps, to the prototyping and industrialization phases.
Handbook of Active Materials for Medical Devices, Andrés Díaz Lantada, PAN Stanford Publishing – CRC Press 2011: This book focuses on all types of biodevices, mainly implantable or chirurgical, used in the diagnosis or treatment of various pathologies, which benefit from the use of active materials such as sensors or actuators. Such active or “intelligent” materials are capable of responding in a controlled way to various external physical or chemical stimuli by changing some of their properties. These materials can be used to design and develop sensors, actuators, and multifunctional systems with a large number of applications for developing biodevices and medical devices. Current work in this field entails problems related to synthesis, characterization, modelling, simulation, processing, and prototyping technologies, as well as device testing and validation, all of which are treated in depth in this book. The research presented will help future developments in medical devices, based on the additional functionalities that the use of active or “intelligent” materials, both as sensors and as actuators, affords. The results offered in the book will help in the industrial expansion of active materials as part of more complex systems.